Oprah showed off her slimmed-down figure as she arrived in Venice for the lavish wedding of Lauren Sanchez and Jeff Bezos on Friday with her friend Gayle King.
The TV personality, 71 – who once topped the scales at 237lbs in 1992 – finally reached her 160lb goal weight in 2023 after undergoing double-knee replacement surgery in 2021.
After vehemently denying she had ever taken weight loss drugs, she finally admitted to taking them in a shock interview.
Oprah lead the pack of celebrities flaunting much smaller physiques, alongside her best friend Gayle, 70, who has also dropped the pounds.
She dressed casually in a blue T-shirt, teamed with a matching pair of fitted leggings and a baseball cap.
Oprah and Gayle had some breakfast at the Gritti Hotel amid the celebrations, which are expected to continue until Sunday.
Oprah (L) showed off her slimmed-down figure as she arrived in Venice for the lavish wedding of Lauren Sanchez and Jeff Bezos on Friday with her friend Gayle King (R)
The TV personality, 71 – who once topped the scales at 237lbs in 1992 – finally reached her 160lb goal weight in 2023 after undergoing double-knee replacement surgery in 2021
A-list stars have flocked to the romantic city to attend the lavish wedding reveling in the opportunity to parade their slimmer bodies amid the Ozempic trend sweeping Hollywood.
Leonardo DiCaprio, 50, looked considerably thinner as he arrived for the celebrations, although his method for recently transforming from tubby to trim remains a mystery.
Kim Kardashian, 44, and her sisters also showcased their impossibly small waistlines.
Her sister Khloe, 41, also showed off her gym-honed figure into a simple black summer dress as she went shopping with her leopard print clad mother Kris Jenner.
But the bride-to-be was not to be outdone – with Sanchez, 55, wearing the most eye-popping corset of all to her pre-wedding party at the Madonna dell Orto cloisters on Thursday night.
The wedding ceremony itself is set to take place on Friday, June 27 – but festivities are already underway in preparation for the big day.
Oprah looked more confident than ever at the pre-wedding party while sporting a purple and white-colored ensemble with small cutouts on the sides that showcased her shrinking midriff.
The former talk show host has showed off her slimmer figure in recent months – such as when she made an appearance at the 2025 Tony Awards in NYC.
The Ozempic wedding! Celebrities including Oprah showed off their skinny waistlines at Lauren Sanchez and Jeff Bezos’ wedding extravaganza in Venice on Thursday wearing a Valentino Garavani dress
Oprah is pictured in August 2019 before her weight loss
Back in 2023, the star admitted to taking weight loss medication and at the time she told People, ‘I now use it as I feel I need it, as a tool to manage not yo-yoing…
‘The fact that there’s a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for.’
Winfrey added, ‘I’m absolutely done with the shaming from other people and particularly myself’ and explained she had recommended weight loss drugs to people before making the choice to also take the medication for herself.
However, despite her weight loss journey being aided by medication, Oprah told the outlet that she also sticks to a fitness regime to also shed pounds, and maintain a lower weight.
And earlier this year in January, the star expressed that taking weight-loss drugs, like Ozempic and Wegovy, helped her realize the truth about ‘thin people.’
Oprah – who has lost nearly 50 pounds with the aid of one of the newly popular weight-loss drugs – was seen arriving to Venice on Thursday
She once again gave a glimpse at her smaller frame as she attended a party later on Thursday while sporting a purple and white-colored ensemble with small cutouts on the sides
Her hair was parted in the middle and effortlessly flowed down past her shoulders in light curl; seen above with Gayle, who has also lost weight recently
Gayle is pictured in December 2022